The Eisenhower School has been designated by the Under Secretary of Defense for Acquisition, Technology, and Logistics to conduct the Senior Acquisition Course for selected students as part of the Defense Acquisition University (DAU). The Senior Acquisition Course is the preeminent course for members of the Acquisition Corps. The course is designed to prepare selected military officers and civilians for senior leadership and staff positions throughout the acquisition community.

The Senior Acquisition Course consists of the entire 10-month Eisenhower School curriculum, complemented by two prescribed elective courses, which address contemporary and future policy issues in the field of acquisition. Senior Acquisition Course students are fully integrated as part of the school's student body a mix of war fighters, operators and joint specialists; plus support, diplomatic and federal agency personnel; international fellows; and representatives of American industry. Students completing the course receive both the Eisenhower School Master's degree and a diploma from Defense Acquisition University.